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What is Palmitoyl Tripeptide-38?

Palmitoyl Tripeptide-38 functions in skincare and cosmetics as an anti-aging peptide.
Palmitoyl Tripeptide-38, trademarked and advertised as MATRIXYL synthe’6 and Volulip, a cosmetic peptide or double-oxidized lipopeptide, consists of three amino acids. This peptide is pro-collagen lipopeptide which rebuilds the skin from the inside where it is needed, soothing wrinkles and skin especially for the forehead, crow’s feet, heads and necks.

More information on Palmitoyl Tripeptide-38

Palmitoyl Tripeptide-38 is the reaction product of palmitic acid and Tripeptide-38.


1. Sanz M T, Campos C, Milani M, Foyaca M, Lamy A, Kurdian K, and Trullas C. Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro‐collagen lipopeptide, creatine, and urea on skin aging signs. Journal of Cosmetic Dermatology. 2016, 15(1): 24-30.

2. Trookman N S, Rizer R L, Ford R, Mehta R, and Gotz V. Clinical assessment of a combination lip treatment to restore moisturization and fullness. J Clin Aesthet Dermatol. 2009, 2(12): 44-48.

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