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What is Pentapeptide-18?

Pentapeptide-18 functions in skincare and cosmetics as a new peptide developed by Lipotec to reduce expression wrinkles and that offers two advantages:

  • A new and alternative in vitro mechanism to fight expression wrinkles
    An additive / synergistic effect to complement the action of Argireline® and other peptides

More information on Pentapeptide-18

Pentapeptide-18’s mechanism mimics in vitro the natural mechanism of enkephalins: it couples to the enkephalin receptor, on the outside of the nerve cells. When Pentapeptide-18 couples to the receptor, a conformational change initiates a cascade inside the neuron that results in a decrease of its excitability: the nerve cell’s activity is “turned down” and the release of acetylcholine is modulated. Muscle contraction will be relaxed and therefore, expression wrinkles will be diminished.


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