Royal jelly’s chemical breakdown is mostly water, proteins, carbohydrates, fats, free amino acids, vitamins, and minerals. Components in royal jelly can function as water-binding agents (Source: www.naturaldatabase.com). Not surprisingly, topical application of this bee-produced ingredient can cause contact dermatitis and irritation. Consuming it is even worse if you’re allergic to it. If you’re allergic to honey, don’t put propolis, honey or royal jelly containing products on your skin. However, it is rarely used in high enough concentrations to cause problems. It’s recommended usage level is between 5%-10%.
Royal jelly is highly unstable and will break down if packaged in a jar that routinely exposes it to light and air. Also, ideally, it requires refrigeration to maintain efficacy.
One study from South Korean concluded that it may have whitening effects. (through down-regulation of tyrosinase expression). Another study claims it may have collagen-enhancing properties. Many of these studies cited were done on mice.
10-Hydroxy-2-decenoic acid (10-HDA) is a major fatty acid component of royal jelly and in one study, evidence was found that 10-HDA could prevent UVA-induced damage and inhibit MMP-1 and MMP-3 expressions. Therefore, 10-HDA may be a potential agent for the prevention and treatment of skin photoageing.
Whitening Effect of Watersoluble Royal Jelly from South Korea.http://www.paulaschoice.com/cosmetic-ingredient-dictionary/definition/royal-jelly
Comparative Immunology, Microbiology and Infectious Diseases, January 1996, pages 31–38
Identification of a collagen production-promoting factor from an extract of royal jelly and its possible mechanism.
10-Hydroxy-2-decenoic acid prevents ultraviolet A-induced damage and matrix metalloproteinases expression in human dermal fibroblasts.
Royal jelly enhances migration of human dermal fibroblasts and alters the levels of cholesterol and sphinganine in an in vitro wound healing model.
Royal jelly reduces melanin synthesis through down-regulation of tyrosinase expression.
Royal jelly protects against ultraviolet B-induced photoaging in human skin fibroblasts via enhancing collagen production.
Topical royal jelly alleviates symptoms of pruritus in a murine model of allergic contact dermatitis.