Propolis is a resinous mixture collected from tree buds by bees and is reflective of the area it comes from (for those of you with pollen allergies). Propolis is said to have antibacterial, antioxidant, wound-healing and anti-inflammatory properties for skin. Propolis and honey slowly release hydrogen peroxide when applied but not enough to damage tissues.
Studies on topical propolis use
Propolis on ulcers
Studies on mice and humans with leg ulcers found that propolis helped in healing of cuts and excision wounds, when compared to 0.001% dexamethasone in a cream base.
Propolis on wound healing
A propolis mouth rinse sped up skin cell repair after tooth extraction but had no effect on socket wound healing. Although, it did have anti-fungal effects in patients with denture stomatitis.
Another general study looking into propolis effects said that it seemed to help oral wound healing.
A gel with 5% propolis was found to help in preventing mouth inflammation and ulceration.
Rinsing with propolis extract decreased bacteria counts and bleeding in patients with periodontitis.
Studies done on eye wounds in rats and rabbits lead to the conclusion that propolis had antimicrobial and antibacterial effects (against acanthamoeba keratitis and staphylococcus aureus keratitis).
One study found mixed results when it tested propolis on burn wounds on pigs.
Antioxidant effects of propolis
Propolis was found to have anesthetic and anti-histamine effects in rats. In mice, it was found that propolis may offer some UV protection.
Antimicrobial Agents and Chemotherapy, May 2002, pages 1302–1309
Induction of oxidative DNA damage by flavonoids of propolis: its mechanism and implication about antioxidant capacity.
Effect of Topical Application of Different Substances on Fibroplasia in Cutaneous Surgical Wounds
Assessment of the mutagenic activity of extracts of brazilian propolis in topical pharmaceutical formulations on Mammalian cells in vitro and in vivo.
Propolis modulates vitronectin, laminin, and heparan sulfate/heparin expression during experimental burn healing*
Topical effect of propolis in the repair of sulcoplasties by the modified Kazanjian technique. Cytological and clinical evaluation.
Application of propolis to dental sockets and skin wounds.
Effect of propolis on mast cells in wound healing.
Mucoadhesive propolis gel for prevention of radiation-induced oral mucositis.
Honey and a mixture of honey, beeswax, and olive oil-propolis extract in treatment of chemotherapy-induced oral mucositis: a randomized controlled pilot study.
Honeybee propolis extract in periodontal treatment: a clinical and microbiological study of propolis in periodontal treatment.
Effect of topical application of Brazilian propolis on scratching behavior induced by compound 48/80 in mice.
Topical ‘Sydney’ propolis protects against UV-radiation-induced inflammation, lipid peroxidation and immune suppression in mouse skin.
The effect of propolis in experimental Acanthamoeba keratitis.