A handful of studies have shown that coenzyme Q10 (CoQ10) may have an effect on skin and the appearance of wrinkles, most notably by reducing UV damage, stimulating healthy collagen production, and reducing substances in damaged skin that wreck havoc on its support structure (Sources: Biofactors, Volume 32, 2008, pages 237–243; and November 2005, pages 179–185;Journal of Cosmetic Dermatology, March 2006, pages 30–38; and www.naturaldatabase.com).
The latest research suggests that topical application of CoQ10 has antioxidant and anti-inflammatory effects. (Sources: Biofactors, September-October 2009, pages 435–441; Journal of Investigative Dermatology, 2005, volume 125, number 4, pages 12–13; and Journal of Dermatological Science, August 2001, Supplement, pages 1–4).
Coenzyme Q(10) enhances dermal elastin expression, inhibits IL-1α production and melanin synthesis in vitro. Source: International Journal of Cosmetic Science; 2012 Jun;34(3):273-9. doi: 10.1111/j.1468-2494.2012.00713.x. Epub 2012 Mar 24.
Chemically, idebenone is an organic compound of the quinone family. It is also promoted commercially as a synthetic analog of coenzyme Q10 (CoQ10).